Hubungan Ekspresi Osteocalcin dan Interleukin-1β dengan Status Inflamasi Periodontal

Periodontitis is inflammation of the periodontal tissue that can cause progressive damage to ligament and alveolar bone. Clinical examination determine degree bone using a probe instrument or probing. Cellular activity in gingival crevicular fluid thought be biomarker inflammatory status tissue. immune responses suggest role cytokines pathogenesis gingivitis periodontitis. The observed this study were protein Osteocalcin Interleukin-1β (IL-1β) (GCF). In study, 67 patients examined for condition their tissues including severity group was divided into 4 groups, namely normal, mild, moderate, severe. Meanwhile, probing samples grouped based on 3 groups. Group I (0-3 mm), II (3.1-5 mm) III (> 5 mm). GCF obtained paper points left sulcus 30 seconds. Then are put cryovial tubes which sent laboratory ELISA test. data expression IL-1β then performed statistical tests. showed significant difference with cases. other hand, it did not show pocket depth. associated